As Portland's homeless youth start to go missing, Nick (David Giuntoli) uncovers a deadly black market supplying the Grimm world with human organs for all types of elixirs. As the investigation heightens, Nick and Juliette (Bitsie Tulloch) befriend a pair of homeless siblings, Hanson (guest star Daryl Sabara, "Spy Kids") and Gracie (guest star Hannah Marks, "Necessary Roughness"), whose friends have gone missing. Russell Hornsby, Silas Weir Mitchell, Sasha Roiz and Reggie Lee also star.